Antihistamine

The most common medicine I was prescribed is antihistamine. To my knowledge, antihistamines have evolved from more classical first generation ones to the non-sedating second generation ones. Antihistamines or more specifically H₁-receptor antagonists will inhibit the action of H₁-receptor to suppress itching and allergy reactions. Histamine is a chemical in our body’s cell that will act on the H₁-receptor, blocking those receptors temporarily to alleviate allergic symptoms, leading to itching and redness. Atarax (Hydroxyzine) is one of the first-generation antihistamines I was prescribed. It is used to relieve anxiety, tension, itching and is very sedative. The sedative effect makes me sleep better. It helps reduce my itching and make me feel relieved at night. During the day, I take the non-sedative one – Zyrtec. Zyrtec is used mainly to relieve sneezing, runny nose and allergic conditions. It contains active ingredient Cetirizine which is known to be more selective for peripheral H₁-receptors, reducing sedation. I was told by my doctor that antihistamine could be taken a little more than the recommended dosage. A tablet a day might not be enough for me if itching is serious and affecting my daily life. However, I would not recommend doing this unless prior advice from the doctor is obtained. I have been taking antihistamines for the past many years. They are not that effective to me anymore as I am almost immune to it. Overreliance on antihistamines is not desirable either. Aside from the two aforementioned brands, I do take Piriton, Polaramine, Claritin and other brands of Cetirizine as well. Piriton (chlorphenamine) is common in Malaysia but it may cause drowsiness and blurred vision and I will take it before sleep. Nonetheless, it is still crucial to consult the doctor before taking any form of medicine or drug.